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You BR, Shin HR, Park WH

In a subgroup of 152 ORLISTAT and 77 placebo patients from the 54-week study, changes in body composition measured by DEXA were similar in both treatment groups with the exception of fat mass, which was significantly reduced in patients treated with ORLISTAT compared to patients treated with placebo (-2.5 kg vs -0.6 kg, p=0.033)

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A number of animal studies indicated CoQ10 can lower oxidative stress in auditory system tissues and protect against hearing loss due to aging, noise exposure, and ototoxic drugs